Caspase-8 gene is frequently inactivated by the frameshift somatic mutation 1225_1226delTG in hepatocellular carcinomas. [electronic resource]
- Oncogene Jan 2005
- 141-7 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0950-9232
10.1038/sj.onc.1208244 doi
Adaptor Proteins, Signal Transducing--metabolism Alleles Apoptosis--genetics Carcinoma, Hepatocellular--enzymology Caspase 8 Caspases--genetics Fas-Associated Death Domain Protein Frameshift Mutation Humans Immunohistochemistry Liver Neoplasms--enzymology Organ Specificity Protein Binding