TY - GEN AU - Thoma,Ralf AU - Schulz-Gasch,Tanja AU - D'Arcy,Brigitte AU - Benz,Jörg AU - Aebi,Johannes AU - Dehmlow,Henrietta AU - Hennig,Michael AU - Stihle,Martine AU - Ruf,Armin TI - Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase SN - 1476-4687 PY - 2004///1217 KW - Anticholesteremic Agents KW - chemistry KW - Benzophenones KW - Catalysis KW - Crystallography, X-Ray KW - Cyclization KW - Drug Design KW - Humans KW - Intramolecular Transferases KW - antagonists & inhibitors KW - Lanosterol KW - Models, Molecular KW - Squalene KW - analogs & derivatives KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1038/nature02993 ER -