Fischbach, Neal A

HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo. [electronic resource] - Blood Feb 2005 - 1456-66 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0006-4971

10.1182/blood-2004-04-1583 doi


Acute Disease
Animals
Bone Marrow Cells--metabolism
Cell Differentiation--genetics
Cell Line, Transformed
Cell Proliferation
Cell Transformation, Neoplastic--pathology
Erythropoiesis--genetics
Female
Homeodomain Proteins--biosynthesis
Karyotyping
Leukemia, Myeloid--blood
Lymphopoiesis--genetics
Mice
Mice, Congenic
Mice, Inbred C57BL
Myeloid Ecotropic Viral Integration Site 1 Protein
Myeloid Progenitor Cells--metabolism
Neoplasm Proteins--physiology
Phenotype
Time Factors