TY  - GEN
AU  - Jiang,Xiuxian
AU  - Zhao,Baoguang
AU  - Britton,Robert
AU  - Lim,Lynette Y
AU  - Leong,Dan
AU  - Sanghera,Jasbinder S
AU  - Zhou,Bin-Bing S
AU  - Piers,Edward
AU  - Andersen,Raymond J
AU  - Roberge,Michel
TI  - Inhibition of Chk1 by the G2 DNA damage checkpoint inhibitor isogranulatimide
SN  - 1535-7163
PY  - 2005///0421
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Catalytic Domain
KW  - Cell Line, Tumor
KW  - Checkpoint Kinase 1
KW  - Crystallography, X-Ray
KW  - Cysteine
KW  - chemistry
KW  - DNA Damage
KW  - Dose-Response Relationship, Drug
KW  - G2 Phase
KW  - Glutamine
KW  - Glycogen Synthase Kinase 3
KW  - metabolism
KW  - Glycogen Synthase Kinase 3 beta
KW  - Humans
KW  - Imidazoles
KW  - Indoles
KW  - antagonists & inhibitors
KW  - Inhibitory Concentration 50
KW  - Maleimides
KW  - Models, Chemical
KW  - Models, Molecular
KW  - Nitrogen
KW  - Phenotype
KW  - Protein Binding
KW  - Protein Kinase C
KW  - Protein Kinase C beta
KW  - Protein Kinases
KW  - Protein Structure, Tertiary
KW  - Time Factors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
ER  -