Park, Moon-Taek

Phytosphingosine in combination with ionizing radiation enhances apoptotic cell death in radiation-resistant cancer cells through ROS-dependent and -independent AIF release. [electronic resource] - Blood Feb 2005 - 1724-33 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-4971

10.1182/blood-2004-07-2938 doi


Active Transport, Cell Nucleus--drug effects
Apoptosis--drug effects
Apoptosis Inducing Factor
Cell Nucleus--drug effects
Clone Cells
Combined Modality Therapy
Enzyme Activation--drug effects
Flavoproteins--metabolism
Gamma Rays
Humans
Intracellular Membranes--drug effects
Jurkat Cells
Membrane Potentials--drug effects
Membrane Proteins--metabolism
Mitochondria--drug effects
Poly(ADP-ribose) Polymerases--metabolism
Proto-Oncogene Proteins c-bcl-2--metabolism
Radiation Tolerance
Reactive Oxygen Species--pharmacology
Sphingosine--analogs & derivatives
bcl-2-Associated X Protein