Celecoxib inhibits angiogenesis by inducing endothelial cell apoptosis in human pancreatic tumor xenografts. [electronic resource]
- Cancer biology & therapy Dec 2004
- 1217-24 p. digital
Publication Type: Journal Article
1538-4047
10.4161/cbt.3.12.1221 doi
Adenocarcinoma--blood supply Animals Anti-Inflammatory Agents, Non-Steroidal--therapeutic use Apoptosis--drug effects Celecoxib Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Cyclooxygenase Inhibitors--therapeutic use Dinoprostone--metabolism Endothelial Cells--metabolism Fibroblast Growth Factor 2--metabolism Group IV Phospholipases A2 Humans Indomethacin--therapeutic use Interleukin-8--metabolism Male Membrane Proteins Mice Mice, Nude Neovascularization, Pathologic--drug therapy Pancreatic Neoplasms--blood supply Phospholipases A--metabolism Phospholipases A2 Prostaglandin-Endoperoxide Synthases--metabolism Pyrazoles--therapeutic use Sulfonamides--therapeutic use Tumor Cells, Cultured Vascular Endothelial Growth Factor A--metabolism Xenograft Model Antitumor Assays