Kakkis, E <br/><br/>
Intrathecal enzyme replacement therapy reduces lysosomal storage in the brain and meninges of the canine model of MPS I.  [electronic resource] 

 -  Molecular genetics and metabolism   
 - 163-74 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1096-7192 
<br/><br/><label>Standard No.: </label>10.1016/j.ymgme.2004.07.003  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Brain--drug effects<br/>Disease Models, Animal<br/>Dogs<br/>Dose-Response Relationship, Drug<br/>Glycosaminoglycans--metabolism<br/>Humans<br/>Iduronidase--administration & dosage<br/>Immune System--drug effects<br/>Injections, Spinal<br/>Lysosomes--drug effects<br/>Meninges--drug effects<br/>Mucopolysaccharidosis I--drug therapy<br/>Recombinant Proteins--administration & dosage<br/>Reference Values<br/>Tissue Distribution