TY - GEN AU - Kim,Seong-Hun AU - Yin,Ye Ingrid AU - Li,Yue-Ming AU - Sisodia,Sangram S TI - Evidence that assembly of an active gamma-secretase complex occurs in the early compartments of the secretory pathway SN - 0021-9258 PY - 2005///0111 KW - Amino Acid Motifs KW - Amyloid Precursor Protein Secretases KW - Amyloid beta-Protein Precursor KW - chemistry KW - Aspartic Acid Endopeptidases KW - Benzophenones KW - pharmacology KW - Binding Sites KW - Biotinylation KW - Blotting, Western KW - Catalysis KW - Cell Line KW - Cell Membrane KW - metabolism KW - Cell-Free System KW - Cross-Linking Reagents KW - DNA, Complementary KW - Endopeptidases KW - Endoplasmic Reticulum KW - Enzyme Inhibitors KW - Epitopes KW - Golgi Apparatus KW - Humans KW - Membrane Proteins KW - Peptide Hydrolases KW - Protein Conformation KW - Protein Structure, Tertiary KW - Receptors, Notch KW - Transfection KW - trans-Golgi Network N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1074/jbc.C400396200 ER -