TY  - GEN
AU  - Hirani,Vandana N
AU  - Raucy,Judy L
AU  - Lasker,Jerome M
TI  - Conversion of the HIV protease inhibitor nelfinavir to a bioactive metabolite by human liver CYP2C19
SN  - 0090-9556
PY  - 2005///0408
KW  - Antibodies, Monoclonal
KW  - pharmacology
KW  - Aryl Hydrocarbon Hydroxylases
KW  - antagonists & inhibitors
KW  - Biotransformation
KW  - Cytochrome P-450 CYP2C19
KW  - Enzyme Inhibitors
KW  - HIV Protease Inhibitors
KW  - pharmacokinetics
KW  - Humans
KW  - Hydroxylation
KW  - In Vitro Techniques
KW  - Kinetics
KW  - Microsomes, Liver
KW  - metabolism
KW  - Mixed Function Oxygenases
KW  - Nelfinavir
KW  - analogs & derivatives
KW  - Omeprazole
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1124/dmd.104.001743
ER  -