Hirani, Vandana N <br/><br/>
Conversion of the HIV protease inhibitor nelfinavir to a bioactive metabolite by human liver CYP2C19.  [electronic resource] 

 -  Drug metabolism and disposition: the biological fate of chemicals  Dec 2004 
 - 1462-7 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0090-9556 
<br/><br/><label>Standard No.: </label>10.1124/dmd.104.001743  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antibodies, Monoclonal--pharmacology<br/>Aryl Hydrocarbon Hydroxylases--antagonists & inhibitors<br/>Biotransformation<br/>Cytochrome P-450 CYP2C19<br/>Enzyme Inhibitors--pharmacology<br/>HIV Protease Inhibitors--pharmacokinetics<br/>Humans<br/>Hydroxylation<br/>In Vitro Techniques<br/>Kinetics<br/>Microsomes, Liver--metabolism<br/>Mixed Function Oxygenases--antagonists & inhibitors<br/>Nelfinavir--analogs & derivatives<br/>Omeprazole--pharmacology