Activation of the RON receptor tyrosine kinase attenuates transforming growth factor-beta1-induced apoptotic death and promotes phenotypic changes in mouse intestinal epithelial cells. [electronic resource]
- Carcinogenesis Jan 2005
- 27-36 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0143-3334
10.1093/carcin/bgh284 doi
Animals Apoptosis--drug effects Blotting, Western Cadherins--metabolism Carrier Proteins--drug effects Caspase 3 Caspases--drug effects Cell Line Enzyme Activation--drug effects Hepatocyte Growth Factor--pharmacology Humans Immunoprecipitation Intestinal Mucosa--drug effects Intracellular Signaling Peptides and Proteins--pharmacology Mice Mitogen-Activated Protein Kinases--drug effects Phenotype Proto-Oncogene Mas Proto-Oncogene Proteins--pharmacology Receptor Protein-Tyrosine Kinases--metabolism Transforming Growth Factor beta--metabolism Transforming Growth Factor beta1 bcl-Associated Death Protein