Shimoyama, Naohito

An antisense oligonucleotide to the N-methyl-D-aspartate (NMDA) subunit NMDAR1 attenuates NMDA-induced nociception, hyperalgesia, and morphine tolerance. [electronic resource] - The Journal of pharmacology and experimental therapeutics Feb 2005 - 834-40 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-3565

10.1124/jpet.104.074856 doi


Analgesics, Opioid--pharmacology
Animals
Autoradiography
Behavior, Animal--drug effects
Dose-Response Relationship, Drug
Drug Tolerance
Excitatory Amino Acid Agonists--pharmacology
Excitatory Amino Acid Antagonists--pharmacology
Formaldehyde
Glycine--metabolism
Hyperalgesia--chemically induced
Indoles--pharmacology
Injections, Spinal
Morphine--pharmacology
N-Methylaspartate--antagonists & inhibitors
Narcotics--pharmacology
Oligonucleotides, Antisense--pharmacology
Pain--chemically induced
Pain Measurement--drug effects
RNA Probes
RNA, Messenger--biosynthesis
Rats
Reaction Time
Receptors, N-Methyl-D-Aspartate--biosynthesis
Spinal Cord--drug effects