Shah, O Jameel <br/><br/>
Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies.  [electronic resource] 

 -  Current biology : CB  Sep 2004 
 - 1650-6 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0960-9822 
<br/><br/><label>Standard No.: </label>10.1016/j.cub.2004.08.026  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Blotting, Northern<br/>Cell Survival--physiology<br/>Cells, Cultured<br/>Down-Regulation<br/>Flow Cytometry<br/>Humans<br/>Immunoblotting<br/>Immunoprecipitation<br/>Insulin Receptor Substrate Proteins<br/>Insulin Resistance--physiology<br/>Insulin-Like Growth Factor I--metabolism<br/>Monomeric GTP-Binding Proteins--metabolism<br/>Neuropeptides--metabolism<br/>Phosphatidylinositol 3-Kinases--metabolism<br/>Phosphoproteins--metabolism<br/>Protein Kinases--metabolism<br/>Proteins--metabolism<br/>Ras Homolog Enriched in Brain Protein<br/>Repressor Proteins--metabolism<br/>Ribosomal Protein S6 Kinases--metabolism<br/>Signal Transduction<br/>TOR Serine-Threonine Kinases<br/>Tuberous Sclerosis--metabolism<br/>Tuberous Sclerosis Complex 1 Protein<br/>Tuberous Sclerosis Complex 2 Protein<br/>Tumor Suppressor Proteins