Rucha, A

Heterologous desensitization of insulin secretion by GIP (glucose-dependent insulinotropic peptide) in INS-1 cells: the significance of Galphai2 and investigations on the mechanism involved. [electronic resource] - Cell biochemistry and function - 205-12 p. digital

Publication Type: Journal Article

0263-6484

10.1002/cbf.1134 doi


1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine--analogs & derivatives
8-Bromo Cyclic Adenosine Monophosphate--analogs & derivatives
Adrenergic alpha-Agonists--pharmacology
Animals
Brimonidine Tartrate
Cell Line, Tumor
Cyclic AMP-Dependent Protein Kinases--antagonists & inhibitors
Enzyme Inhibitors--pharmacology
GTP-Binding Protein alpha Subunit, Gi2
GTP-Binding Protein alpha Subunits, Gi-Go--genetics
Gastric Inhibitory Polypeptide--pharmacology
Gene Expression--drug effects
Glucagon--metabolism
Glucagon-Like Peptide 1
Immunosuppressive Agents--pharmacology
Insulin--metabolism
Insulin Secretion
Islets of Langerhans--cytology
Peptide Fragments--metabolism
Protein Precursors--metabolism
Proto-Oncogene Proteins--genetics
Quinoxalines--pharmacology
RNA, Messenger--metabolism
Rats
Second Messenger Systems--drug effects
Tacrolimus--pharmacology
Thionucleotides--pharmacology