TY  - GEN
AU  - Williams,Terence M
AU  - Medina,Freddy
AU  - Badano,Ines
AU  - Hazan,Rachel B
AU  - Hutchinson,John
AU  - Muller,William J
AU  - Chopra,Neeru G
AU  - Scherer,Philipp E
AU  - Pestell,Richard G
AU  - Lisanti,Michael P
TI  - Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion
SN  - 0021-9258
PY  - 2005///0111
KW  - Animals
KW  - Caveolin 1
KW  - Caveolins
KW  - genetics
KW  - Cell Line, Tumor
KW  - Cell Membrane
KW  - metabolism
KW  - Cell Movement
KW  - Cells, Cultured
KW  - Collagen
KW  - pharmacology
KW  - Cyclin D1
KW  - biosynthesis
KW  - Disease Progression
KW  - Drug Combinations
KW  - Electrophoresis, Polyacrylamide Gel
KW  - Enzyme Activation
KW  - Female
KW  - Gene Expression Regulation, Neoplastic
KW  - Immunoblotting
KW  - Inhibitory Concentration 50
KW  - Laminin
KW  - Lung Neoplasms
KW  - secondary
KW  - Male
KW  - Mammary Neoplasms, Animal
KW  - Mammary Tumor Virus, Mouse
KW  - Matrix Metalloproteinase 2
KW  - Matrix Metalloproteinase 9
KW  - Mice
KW  - Mice, Transgenic
KW  - Microscopy, Fluorescence
KW  - Mitogen-Activated Protein Kinase 1
KW  - Mitogen-Activated Protein Kinase 3
KW  - Mutation
KW  - Neoplasm Invasiveness
KW  - Neoplasm Metastasis
KW  - Peptides
KW  - chemistry
KW  - Phosphorylation
KW  - Proteoglycans
KW  - Recombinant Proteins
KW  - Retinoblastoma Protein
KW  - Retroviridae
KW  - Time Factors
KW  - Up-Regulation
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1074/jbc.M409214200
ER  -