Gentamicin binds to the lectin site of calreticulin and inhibits its chaperone activity. [electronic resource]
- Biochemical and biophysical research communications Oct 2004
- 281-7 p. digital
Publication Type: Journal Article
0006-291X
10.1016/j.bbrc.2004.08.099 doi
Animals Anti-Bacterial Agents--pharmacology Binding Sites Calreticulin--chemistry Cattle Chromatography Dose-Response Relationship, Drug Electrophoresis, Polyacrylamide Gel Endoplasmic Reticulum--metabolism Gentamicins--pharmacology Humans Kidney--metabolism Lectins--chemistry Microsomes--metabolism Molecular Chaperones--chemistry Mutation Oligosaccharides--chemistry Oxygen--chemistry Plasmids--metabolism Protein Binding Protein Disulfide-Isomerases--chemistry Protein Folding Protein Structure, Tertiary Recombinant Proteins--chemistry Sepharose--pharmacology Time Factors alpha 1-Antitrypsin--chemistry alpha-Mannosidase--chemistry