TY - GEN AU - Chen,Chen AU - Wilcoxen,Keith M AU - Huang,Charles Q AU - Xie,Yun-Feng AU - McCarthy,James R AU - Webb,Thomas R AU - Zhu,Yun-Fei AU - Saunders,John AU - Liu,Xin-Jun AU - Chen,Ta-Kung AU - Bozigian,Haig AU - Grigoriadis,Dimitri E TI - Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and structure--activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists SN - 0022-2623 PY - 2004///1007 KW - Adrenocorticotropic Hormone KW - metabolism KW - Animals KW - Corticotropin-Releasing Hormone KW - pharmacology KW - Cyclic AMP KW - Drug Design KW - Inhibitory Concentration 50 KW - Male KW - Mice KW - Molecular Structure KW - Pyrimidines KW - administration & dosage KW - Rats KW - Rats, Sprague-Dawley KW - Receptors, Corticotropin-Releasing Hormone KW - antagonists & inhibitors KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/jm040058e ER -