Chen, Chen <br/><br/>
Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and structure--activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists.  [electronic resource] 

 -  Journal of medicinal chemistry  Sep 2004 
 - 4787-98 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm040058e  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adrenocorticotropic Hormone--metabolism<br/>Animals<br/>Corticotropin-Releasing Hormone--pharmacology<br/>Cyclic AMP--metabolism<br/>Drug Design<br/>Inhibitory Concentration 50<br/>Male<br/>Mice<br/>Molecular Structure<br/>Pyrimidines--administration & dosage<br/>Rats<br/>Rats, Sprague-Dawley<br/>Receptors, Corticotropin-Releasing Hormone--antagonists & inhibitors<br/>Structure-Activity Relationship