TY - GEN AU - O'Meara,Sarah J AU - Kinsella,B Therese TI - Investigation of the effect of the farnesyl protein transferase inhibitor R115777 on isoprenylation and intracellular signalling by the prostacyclin receptor SN - 0007-1188 PY - 2005///0422 KW - Alkyl and Aryl Transferases KW - antagonists & inhibitors KW - Animals KW - Calcium KW - metabolism KW - Cell Line KW - Cell Survival KW - drug effects KW - Cyclic AMP KW - Dose-Response Relationship, Drug KW - Drug Evaluation, Preclinical KW - methods KW - Enzyme Inhibitors KW - pharmacology KW - Humans KW - Iloprost KW - Ireland KW - Mice KW - Molecular Chaperones KW - Organophosphonates KW - Protein Prenylation KW - Quinolones KW - chemistry KW - Receptor Cross-Talk KW - Receptors, Prostaglandin KW - classification KW - Time Factors KW - Transfection KW - Transferases KW - Tritium N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/sj.bjp.0705956 ER -