TY - GEN AU - Kharasch,Evan D AU - Whittington,Dale AU - Hoffer,Christine TI - Influence of hepatic and intestinal cytochrome P4503A activity on the acute disposition and effects of oral transmucosal fentanyl citrate SN - 0003-3022 PY - 2004///0920 KW - Adult KW - Analgesics, Opioid KW - administration & dosage KW - Antibiotics, Antitubercular KW - pharmacology KW - Antiemetics KW - Area Under Curve KW - Aryl Hydrocarbon Hydroxylases KW - metabolism KW - Beverages KW - Chromatography, High Pressure Liquid KW - Citrus KW - Cross-Over Studies KW - Cytochrome P-450 CYP3A KW - Drug Interactions KW - Female KW - Fentanyl KW - Food-Drug Interactions KW - Half-Life KW - Humans KW - Intestines KW - enzymology KW - Liver KW - Male KW - Oxidoreductases, N-Demethylating KW - Pupil KW - drug effects KW - Rifampin KW - Spectrometry, Mass, Electrospray Ionization KW - Troleandomycin N1 - Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1097/00000542-200409000-00022 ER -