TY  - GEN
AU  - Jin,Yong-Ri
AU  - Cho,Mi-Ra
AU  - Ryu,Chung-Kyu
AU  - Chung,Jin-Ho
AU  - Yuk,Dong-Yeon
AU  - Hong,Jin-Tae
AU  - Lee,Kyung-Sup
AU  - Lee,Jung-Jin
AU  - Lee,Mi-Yea
AU  - Lim,Yong
AU  - Yun,Yeo-Pyo
TI  - Antiplatelet activity of J78 (2-Chloro-3-[2'-bromo, 4'-fluoro-phenyl]-amino-8-hydroxy-1,4-naphthoquinone), an antithrombotic agent, is mediated by thromboxane (TX) A2 receptor blockade with TXA2 synthase inhibition and suppression of cytosolic Ca2+ mobilization
SN  - 0022-3565
PY  - 2005///0413
KW  - 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid
KW  - metabolism
KW  - Animals
KW  - Arachidonic Acid
KW  - Blood Platelets
KW  - drug effects
KW  - Calcium
KW  - Collagen
KW  - pharmacology
KW  - Male
KW  - Naphthoquinones
KW  - Platelet Aggregation
KW  - Prostaglandins D
KW  - Rabbits
KW  - Thromboxane A2
KW  - Thromboxane B2
KW  - Thromboxane-A Synthase
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1124/jpet.104.073718
ER  -