Jin, Yong-Ri <br/><br/>
Antiplatelet activity of J78 (2-Chloro-3-[2'-bromo, 4'-fluoro-phenyl]-amino-8-hydroxy-1,4-naphthoquinone), an antithrombotic agent, is mediated by thromboxane (TX) A2 receptor blockade with TXA2 synthase inhibition and suppression of cytosolic Ca2+ mobilization.  [electronic resource] 

 -  The Journal of pharmacology and experimental therapeutics  Jan 2005 
 - 214-9 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-3565 
<br/><br/><label>Standard No.: </label>10.1124/jpet.104.073718  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>12-Hydroxy-5,8,10,14-eicosatetraenoic Acid--metabolism<br/>Animals<br/>Arachidonic Acid--metabolism<br/>Blood Platelets--drug effects<br/>Calcium--metabolism<br/>Collagen--pharmacology<br/>Male<br/>Naphthoquinones--pharmacology<br/>Platelet Aggregation--drug effects<br/>Prostaglandins D<br/>Rabbits<br/>Thromboxane A2--metabolism<br/>Thromboxane B2--metabolism<br/>Thromboxane-A Synthase--metabolism