TY  - GEN
AU  - Doucet,Nicolas
AU  - De Wals,Pierre-Yves
AU  - Pelletier,Joelle N
TI  - Site-saturation mutagenesis of Tyr-105 reveals its importance in substrate stabilization and discrimination in TEM-1 beta-lactamase
SN  - 0021-9258
PY  - 2004///1130
KW  - Binding Sites
KW  - Computer Simulation
KW  - Escherichia coli
KW  - drug effects
KW  - Kinetics
KW  - Microbial Sensitivity Tests
KW  - Models, Molecular
KW  - Protein Conformation
KW  - Structure-Activity Relationship
KW  - beta-Lactamases
KW  - chemistry
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M407606200
ER  -