Doucet, Nicolas <br/><br/>
Site-saturation mutagenesis of Tyr-105 reveals its importance in substrate stabilization and discrimination in TEM-1 beta-lactamase.  [electronic resource] 

 -  The Journal of biological chemistry  Oct 2004 
 - 46295-303 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0021-9258 
<br/><br/><label>Standard No.: </label>10.1074/jbc.M407606200  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Binding Sites<br/>Computer Simulation<br/>Escherichia coli--drug effects<br/>Kinetics<br/>Microbial Sensitivity Tests<br/>Models, Molecular<br/>Protein Conformation<br/>Structure-Activity Relationship<br/>beta-Lactamases--chemistry