Zucker, Birgit

Gabapentin-lactam, but not gabapentin, reduces protein aggregates and improves motor performance in a transgenic mouse model of Huntington's disease. [electronic resource] - Naunyn-Schmiedeberg's archives of pharmacology Aug 2004 - 131-9 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0028-1298

10.1007/s00210-004-0959-9 doi


Amines--therapeutic use
Animals
Anticonvulsants--therapeutic use
Aza Compounds--blood
Corpus Striatum--metabolism
Cyclohexanecarboxylic Acids--therapeutic use
Disease Models, Animal
Female
Gabapentin
Hippocampus--metabolism
Huntington Disease--drug therapy
Injections, Subcutaneous
Male
Mice
Mice, Transgenic
Motor Activity--drug effects
Neuroprotective Agents--therapeutic use
Spiro Compounds--blood
Survival Rate
gamma-Aminobutyric Acid--therapeutic use