Chen, Ching-Chow

Flavonoids inhibit tumor necrosis factor-alpha-induced up-regulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: structure-activity relationships. [electronic resource] - Molecular pharmacology Sep 2004 - 683-93 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0026-895X

10.1124/mol.66.3. doi


Apigenin
Drug Interactions
Epithelial Cells--drug effects
Flavonoids--pharmacology
Flavonols--pharmacology
Gene Expression Regulation--drug effects
Humans
I-kappa B Kinase
Intercellular Adhesion Molecule-1
JNK Mitogen-Activated Protein Kinases
Kaempferols--pharmacology
Luteolin
Mitogen-Activated Protein Kinases--genetics
NF-kappa B--metabolism
Protein Kinases--metabolism
Protein Serine-Threonine Kinases--metabolism
Proto-Oncogene Proteins c-fos--genetics
RNA, Messenger--drug effects
Transcription Factor AP-1--physiology
Tumor Cells, Cultured
Tumor Necrosis Factor-alpha--pharmacology
U937 Cells
Up-Regulation