TY  - GEN
AU  - Liu,David Q
AU  - Karanam,Bindhu V
AU  - Doss,George A
AU  - Sidler,Rick R
AU  - Vincent,Stella H
AU  - Hop,Cornelis E C A
TI  - In vitro metabolism of MK-0767 [(+/-)-5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[(4-trifluoromethyl)-phenyl] methyl]benzamide], a peroxisome proliferator-activated receptor alpha/gamma agonist. II. Identification of metabolites by liquid chromatography-tandem mass spectrometry
SN  - 0090-9556
PY  - 2005///0623
KW  - Animals
KW  - Carbon Radioisotopes
KW  - Chromatography, Liquid
KW  - methods
KW  - Cytochrome P-450 CYP3A
KW  - Cytochrome P-450 Enzyme System
KW  - genetics
KW  - Dogs
KW  - Drug Evaluation, Preclinical
KW  - Glucuronides
KW  - chemistry
KW  - Haplorhini
KW  - Hepatocytes
KW  - cytology
KW  - Humans
KW  - Mass Spectrometry
KW  - Microsomes, Liver
KW  - drug effects
KW  - NADP
KW  - metabolism
KW  - PPAR alpha
KW  - PPAR gamma
KW  - Rats
KW  - S-Adenosylmethionine
KW  - Sulfhydryl Compounds
KW  - Thiazoles
KW  - Thiazolidinediones
N1  - Publication Type: Comparative Study; Journal Article
UR  - https://doi.org/10.1124/dmd.104.000059
ER  -