The proteasome inhibitor, MG132, promotes the reprogramming of translation in C2C12 myoblasts and facilitates the association of hsp25 with the eIF4F complex. [electronic resource]
- European journal of biochemistry Sep 2004
- 3596-611 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0014-2956
10.1111/j.0014-2956.2004.04306.x doi
Animals Cell Line Cell-Free System Crystallins--metabolism Cysteine Endopeptidases--metabolism Cysteine Proteinase Inhibitors--pharmacology Eukaryotic Initiation Factor-4F--metabolism Gene Expression Regulation Heat-Shock Proteins--metabolism Leupeptins--pharmacology Mice Mitogen-Activated Protein Kinases--metabolism Molecular Chaperones Multienzyme Complexes--antagonists & inhibitors Myoblasts--cytology Neoplasm Proteins--metabolism Phosphorylation Proteasome Endopeptidase Complex Protein Binding Protein Biosynthesis--drug effects RNA Caps Signal Transduction--physiology p38 Mitogen-Activated Protein Kinases