Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2. [electronic resource]
- Molecular and cellular biology Sep 2004
- 7524-37 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0270-7306
10.1128/MCB.24.17.7524-7537.2004 doi
Amino Acid Motifs Animals Cell Line Cysteine Endopeptidases--metabolism DNA-Binding Proteins--genetics Humans JNK Mitogen-Activated Protein Kinases Mitogen-Activated Protein Kinases--metabolism Multienzyme Complexes--metabolism Neoplasms--genetics Proteasome Endopeptidase Complex Protein Binding Protein Processing, Post-Translational RNA Interference Recombinant Fusion Proteins--genetics S-Phase Kinase-Associated Proteins--genetics Signal Transduction--physiology Smad4 Protein Trans-Activators--genetics Ubiquitin--metabolism Ubiquitin-Protein Ligases--genetics p38 Mitogen-Activated Protein Kinases