Sun, Haiying <br/><br/>
Structure-based design, synthesis, and evaluation of conformationally constrained mimetics of the second mitochondria-derived activator of caspase that target the X-linked inhibitor of apoptosis protein/caspase-9 interaction site.  [electronic resource] 

 -  Journal of medicinal chemistry  Aug 2004 
 - 4147-50 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm0499108  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Motifs<br/>Apoptosis--drug effects<br/>Apoptosis Regulatory Proteins<br/>Carrier Proteins--chemistry<br/>Caspase 9<br/>Caspases--metabolism<br/>Cell Line, Tumor<br/>Cyclization<br/>Heterocyclic Compounds, 2-Ring--chemical synthesis<br/>Humans<br/>Intracellular Signaling Peptides and Proteins<br/>Mitochondrial Proteins--chemistry<br/>Models, Molecular<br/>Molecular Conformation<br/>Molecular Mimicry<br/>Oligopeptides--chemistry<br/>Protein Binding<br/>Protein Structure, Tertiary<br/>Proteins--metabolism<br/>Structure-Activity Relationship<br/>X-Linked Inhibitor of Apoptosis Protein