Li, Tsai-Kun <br/><br/>
Drug targeting of HIV-1 RNA.DNA hybrid structures: thermodynamics of recognition and impact on reverse transcriptase-mediated ribonuclease H activity and viral replication.  [electronic resource] 

 -  Biochemistry  Aug 2004 
 - 9732-42 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0006-2960 
<br/><br/><label>Standard No.: </label>10.1021/bi0497345  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aminoglycosides--pharmacology<br/>Binding, Competitive<br/>Circular Dichroism<br/>DNA, Viral--antagonists & inhibitors<br/>Drug Delivery Systems--methods<br/>Enzyme Activation--genetics<br/>HIV Reverse Transcriptase--antagonists & inhibitors<br/>HIV-1--drug effects<br/>Humans<br/>Hydrolysis--drug effects<br/>Neomycin--metabolism<br/>Nucleic Acid Conformation<br/>Nucleic Acid Heteroduplexes--antagonists & inhibitors<br/>Paromomycin--metabolism<br/>RNA, Viral--antagonists & inhibitors<br/>Reverse Transcriptase Inhibitors--metabolism<br/>Ribonuclease H--antagonists & inhibitors<br/>Ribostamycin--metabolism<br/>Thermodynamics<br/>Virus Replication--genetics