Nomura, S

Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia. [electronic resource] - Gene therapy Oct 2004 - 1540-8 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

0969-7128

10.1038/sj.gt.3302310 doi


Adenoviridae--genetics
Animals
Arteriosclerosis--prevention & control
Base Sequence
Disease Progression
Genetic Therapy--methods
Genetic Vectors--administration & dosage
Hyperlipoproteinemia Type II--immunology
Mice
Mice, Knockout
Models, Animal
Molecular Sequence Data
Receptors, LDL--genetics
T-Lymphocytes, Helper-Inducer--immunology
Time Factors
Transduction, Genetic--methods