Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia. [electronic resource]
- Gene therapy Oct 2004
- 1540-8 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
0969-7128
10.1038/sj.gt.3302310 doi
Adenoviridae--genetics Animals Arteriosclerosis--prevention & control Base Sequence Disease Progression Genetic Therapy--methods Genetic Vectors--administration & dosage Hyperlipoproteinemia Type II--immunology Mice Mice, Knockout Models, Animal Molecular Sequence Data Receptors, LDL--genetics T-Lymphocytes, Helper-Inducer--immunology Time Factors Transduction, Genetic--methods