Chin, Paul C <br/><br/>
The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a MEK-ERK and Akt-independent mechanism.  [electronic resource] 

 -  Journal of neurochemistry  Aug 2004 
 - 595-608 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0022-3042 
<br/><br/><label>Standard No.: </label>10.1111/j.1471-4159.2004.02530.x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Cell Death--drug effects<br/>Cells, Cultured<br/>Disease Models, Animal<br/>Enzyme Inhibitors--pharmacology<br/>Farnesol--analogs & derivatives<br/>Huntington Disease--chemically induced<br/>Indoles--pharmacology<br/>Mitogen-Activated Protein Kinase Kinases--antagonists & inhibitors<br/>Mitogen-Activated Protein Kinases--antagonists & inhibitors<br/>Neurodegenerative Diseases--chemically induced<br/>Neurons--cytology<br/>Neuroprotective Agents--pharmacology<br/>Neurotoxins<br/>Nitro Compounds<br/>Phenols--pharmacology<br/>Propionates<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Proto-Oncogene Proteins--antagonists & inhibitors<br/>Proto-Oncogene Proteins c-akt<br/>Proto-Oncogene Proteins c-raf--antagonists & inhibitors<br/>Rats<br/>Rats, Sprague-Dawley<br/>Salicylates--pharmacology<br/>Signal Transduction--drug effects