Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death. [electronic resource]
- Molecular and cellular biology Aug 2004
- 6592-607 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
0270-7306
10.1128/MCB.24.15.6592-6607.2004 doi
Antineoplastic Agents, Phytogenic--pharmacology Apoptosis Blotting, Western Calcium--metabolism Caspase 3 Caspase 8 Caspases--metabolism Cell Death Cell Line Cell Line, Tumor Cell Membrane--metabolism Cell-Free System Centrifugation, Density Gradient Dose-Response Relationship, Drug Down-Regulation Endopeptidase K--metabolism Endoplasmic Reticulum--metabolism Enzyme Activation Etoposide--pharmacology Humans Jurkat Cells Membrane Proteins--metabolism Microscopy, Fluorescence Mitochondria--metabolism Models, Biological Protein Binding Protein Structure, Tertiary RNA, Small Interfering--metabolism Salts--pharmacology Subcellular Fractions--metabolism Sucrose--pharmacology Transfection