TY  - GEN
AU  - Sever,Navdar
AU  - Lee,Peter C W
AU  - Song,Bao-Liang
AU  - Rawson,Robert B
AU  - Debose-Boyd,Russell A
TI  - Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
SN  - 0021-9258
PY  - 2004///1124
KW  - Animals
KW  - CCAAT-Enhancer-Binding Proteins
KW  - CHO Cells
KW  - metabolism
KW  - Cell Line
KW  - Cell Nucleus
KW  - Cholesterol
KW  - Cricetinae
KW  - DNA
KW  - chemistry
KW  - DNA-Binding Proteins
KW  - Diphosphonates
KW  - pharmacology
KW  - Dose-Response Relationship, Drug
KW  - Endoplasmic Reticulum
KW  - Fatty Acids
KW  - Fibroblasts
KW  - Humans
KW  - Hydroxymethylglutaryl CoA Reductases
KW  - Immunoblotting
KW  - Intracellular Signaling Peptides and Proteins
KW  - Lipid Metabolism
KW  - Membrane Proteins
KW  - genetics
KW  - Models, Biological
KW  - Mutagenesis, Site-Directed
KW  - Mutation
KW  - Peptides
KW  - Plasmids
KW  - RNA Interference
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Sterol Regulatory Element Binding Protein 1
KW  - Sterols
KW  - Subcellular Fractions
KW  - Temperature
KW  - Time Factors
KW  - Transcription Factors
KW  - Transfection
KW  - Ubiquitin
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1074/jbc.M406406200
ER  -