Green, B D

Comparative effects of GLP-1 and GIP on cAMP production, insulin secretion, and in vivo antidiabetic actions following substitution of Ala8/Ala2 with 2-aminobutyric acid. [electronic resource] - Archives of biochemistry and biophysics Aug 2004 - 136-43 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0003-9861

10.1016/j.abb.2004.05.005 doi


Adenylyl Cyclases--metabolism
Alanine--chemistry
Aminobutyrates--pharmacology
Animals
Cells, Cultured
Chromatography, High Pressure Liquid
Cyclic AMP--metabolism
Diabetes Mellitus--drug therapy
Dipeptidyl Peptidase 4--chemistry
Dose-Response Relationship, Drug
Gastric Inhibitory Polypeptide--chemistry
Glucagon--chemistry
Glucagon-Like Peptide 1
Glucose--metabolism
Humans
Insulin--metabolism
Insulin Secretion
Islets of Langerhans--metabolism
Mice
Mice, Obese
Models, Chemical
Peptide Fragments--chemistry
Peptides--chemistry
Protein Precursors--chemistry
Protein Structure, Tertiary
Spectrometry, Mass, Electrospray Ionization
Time Factors