TY  - GEN
AU  - Feldstein,Ariel E
AU  - Werneburg,Nathan W
AU  - Canbay,Ali
AU  - Guicciardi,Maria Eugenia
AU  - Bronk,Steven F
AU  - Rydzewski,Robert
AU  - Burgart,Laurence J
AU  - Gores,Gregory J
TI  - Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway
SN  - 0270-9139
PY  - 2004///0727
KW  - Animals
KW  - Antigens, CD
KW  - metabolism
KW  - Cathepsin B
KW  - Cells, Cultured
KW  - Cytosol
KW  - Diet
KW  - adverse effects
KW  - Drug Combinations
KW  - Fatty Acids, Nonesterified
KW  - physiology
KW  - Fatty Liver
KW  - etiology
KW  - Humans
KW  - Liver
KW  - drug effects
KW  - Lysosomes
KW  - Mice
KW  - Mice, Knockout
KW  - NF-kappa B
KW  - Oleic Acid
KW  - poisoning
KW  - Palmitates
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-bcl-2
KW  - Receptors, Tumor Necrosis Factor
KW  - Receptors, Tumor Necrosis Factor, Type I
KW  - Severity of Illness Index
KW  - Tissue Distribution
KW  - Tumor Necrosis Factor-alpha
KW  - bcl-2-Associated X Protein
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1002/hep.20283
ER  -