TY - GEN AU - Yang,Lin AU - Dan,Han C AU - Sun,Mei AU - Liu,Qiyuan AU - Sun,Xia-meng AU - Feldman,Richard I AU - Hamilton,Andrew D AU - Polokoff,Mark AU - Nicosia,Santo V AU - Herlyn,Meenhard AU - Sebti,Said M AU - Cheng,Jin Q TI - Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt SN - 0008-5472 PY - 2004///0826 KW - Animals KW - Apoptosis KW - drug effects KW - Cell Division KW - Cell Line, Tumor KW - Cyclic AMP-Dependent Protein Kinases KW - antagonists & inhibitors KW - Enzyme Inhibitors KW - pharmacology KW - Female KW - Humans KW - Immediate-Early Proteins KW - JNK Mitogen-Activated Protein Kinases KW - MAP Kinase Signaling System KW - Mice KW - Mice, Nude KW - Mitogen-Activated Protein Kinases KW - NIH 3T3 Cells KW - Nuclear Proteins KW - Nucleosides KW - Protein Kinase C KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-akt KW - Pyridazines KW - Signal Transduction KW - Substrate Specificity KW - Xenograft Model Antitumor Assays KW - p38 Mitogen-Activated Protein Kinases N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1158/0008-5472.CAN-04-0343 ER -