TY - GEN AU - Huang,Wei-Chien AU - Chan,Shu-Ting AU - Yang,Tzu-Lin AU - Tzeng,Cherng-Chyi AU - Chen,Ching-Chow TI - Inhibition of ICAM-1 gene expression, monocyte adhesion and cancer cell invasion by targeting IKK complex: molecular and functional study of novel alpha-methylene-gamma-butyrolactone derivatives SN - 0143-3334 PY - 2004///1109 KW - 4-Butyrolactone KW - analogs & derivatives KW - Anti-Ulcer Agents KW - pharmacology KW - Cell Adhesion KW - drug effects KW - Cyclooxygenase 2 KW - Electrophoretic Mobility Shift Assay KW - Epithelial Cells KW - Gene Expression Regulation KW - Humans KW - I-kappa B Kinase KW - Intercellular Adhesion Molecule-1 KW - genetics KW - Isoenzymes KW - metabolism KW - Luciferases KW - Matrix Metalloproteinase 9 KW - Membrane Proteins KW - Mitogen-Activated Protein Kinase 1 KW - Mitogen-Activated Protein Kinase 3 KW - Mitogen-Activated Protein Kinases KW - Monocytes KW - NF-kappa B KW - Neoplasm Invasiveness KW - pathology KW - Phosphorylation KW - Promoter Regions, Genetic KW - Prostaglandin-Endoperoxide Synthases KW - Protein Serine-Threonine Kinases KW - Reverse Transcriptase Polymerase Chain Reaction KW - Tumor Necrosis Factor-alpha KW - U937 Cells KW - p38 Mitogen-Activated Protein Kinases KW - NF-kappaB-Inducing Kinase N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/carcin/bgh211 ER -