TY - GEN AU - Lakos,Gabriella AU - Takagawa,Shinsuke AU - Chen,Shu-Jen AU - Ferreira,Ahalia M AU - Han,Gangwen AU - Masuda,Koichi AU - Wang,Xiao-Jing AU - DiPietro,Luisa A AU - Varga,John TI - Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma SN - 0002-9440 PY - 2004///0903 KW - Actins KW - biosynthesis KW - Animals KW - Bleomycin KW - pharmacology KW - Blotting, Western KW - Cells, Cultured KW - Collagen KW - Connective Tissue Growth Factor KW - Disease Models, Animal KW - Fibroblasts KW - drug effects KW - Fibronectins KW - Fibrosis KW - chemically induced KW - Flow Cytometry KW - Gene Expression Regulation KW - Gene Targeting KW - Hydroxyproline KW - analysis KW - Immediate-Early Proteins KW - Immunohistochemistry KW - In Situ Hybridization KW - Intercellular Signaling Peptides and Proteins KW - metabolism KW - Mice KW - Mice, Knockout KW - Scleroderma, Systemic KW - Signal Transduction KW - Skin KW - chemistry KW - Trans-Activators KW - genetics KW - Transforming Growth Factor beta N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1016/s0002-9440(10)63289-0 ER -