Model system for high-throughput screening of novel human immunodeficiency virus protease inhibitors in Escherichia coli. [electronic resource]
- Antimicrobial agents and chemotherapy Jul 2004
- 2437-47 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0066-4804
10.1128/AAC.48.7.2437-2447.2004 doi
Amides--metabolism Blotting, Western Cost-Benefit Analysis Dose-Response Relationship, Drug Drug Evaluation, Preclinical--economics Escherichia coli--drug effects HIV Protease Inhibitors--pharmacology HIV-1--drug effects Humans Mutagenesis Plasmids--genetics Reproducibility of Results Reverse Transcriptase Polymerase Chain Reaction beta-Galactosidase--metabolism