Kaneider, Nicole C
The immune modulator FTY720 targets sphingosine-kinase-dependent migration of human monocytes in response to amyloid beta-protein and its precursor. [electronic resource]
- FASEB journal : official publication of the Federation of American Societies for Experimental Biology Aug 2004
- 1309-11 p. digital
Publication Type: Comparative Study; Journal Article
ISSN: 1530-6860
Standard No.: 10.1096/fj.03-1050fje doi
Subjects--Topical Terms: 1-Methyl-3-isobutylxanthine--pharmacology Amyloid beta-Peptides--pharmacology Amyloid beta-Protein Precursor--pharmacology Androstadienes--pharmacology Bombesin--pharmacology Calcitonin Gene-Related Peptide--pharmacology Cell Movement--drug effects Chemotaxis, Leukocyte--drug effects Cholera Toxin--pharmacology Drug Evaluation, Preclinical Enzyme Inhibitors--pharmacology Fingolimod Hydrochloride Gene Expression Regulation--drug effects Heterotrimeric GTP-Binding Proteins--physiology Humans Immunologic Factors--pharmacology Indoles--pharmacology Leukocytes, Mononuclear--cytology Maleimides--pharmacology N-Formylmethionine Leucyl-Phenylalanine--pharmacology Neuropeptides--pharmacology Pertussis Toxin--pharmacology Phosphoinositide-3 Kinase Inhibitors Phosphorylation--drug effects Phosphotransferases (Alcohol Group Acceptor)--antagonists & inhibitors Propylene Glycols--pharmacology Protein Kinase Inhibitors--pharmacology Protein Processing, Post-Translational--drug effects RNA, Messenger--biosynthesis Receptors, Lysosphingolipid--agonists Secretogranin II Sphingosine--analogs & derivatives Staurosporine--pharmacology Tyrphostins--pharmacology Vasoactive Intestinal Peptide--pharmacology Wortmannin