TY - GEN AU - Jang,Byeong-Churl AU - Paik,Ji-Hye AU - Jeong,Hye-Yun AU - Oh,Hyun-Ji AU - Park,Jong-Wook AU - Kwon,Taeg Kyu AU - Song,Dae-Kyu AU - Park,Jong-Gu AU - Kim,Sang-Pyo AU - Bae,Jae-Hoon AU - Mun,Kyo-Chul AU - Suh,Min-Ho AU - Yoshida,Minoru AU - Suh,Seong-Il TI - Leptomycin B-induced apoptosis is mediated through caspase activation and down-regulation of Mcl-1 and XIAP expression, but not through the generation of ROS in U937 leukemia cells SN - 0006-2952 PY - 2004///0802 KW - Antibiotics, Antineoplastic KW - pharmacology KW - Apoptosis KW - Caspases KW - metabolism KW - Cell Survival KW - Down-Regulation KW - Enzyme Activation KW - Fatty Acids, Unsaturated KW - chemistry KW - Gene Expression KW - Humans KW - Leukemia KW - pathology KW - Myeloid Cell Leukemia Sequence 1 Protein KW - Neoplasm Proteins KW - Proteins KW - Proto-Oncogene Proteins c-bcl-2 KW - Reactive Oxygen Species KW - U937 Cells KW - X-Linked Inhibitor of Apoptosis Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bcp.2004.03.007 ER -