Jang, Byeong-Churl <br/><br/>
Leptomycin B-induced apoptosis is mediated through caspase activation and down-regulation of Mcl-1 and XIAP expression, but not through the generation of ROS in U937 leukemia cells.  [electronic resource] 

 -  Biochemical pharmacology  Jul 2004 
 - 263-74 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0006-2952 
<br/><br/><label>Standard No.: </label>10.1016/j.bcp.2004.03.007  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antibiotics, Antineoplastic--pharmacology<br/>Apoptosis<br/>Caspases--metabolism<br/>Cell Survival<br/>Down-Regulation<br/>Enzyme Activation<br/>Fatty Acids, Unsaturated--chemistry<br/>Gene Expression<br/>Humans<br/>Leukemia--pathology<br/>Myeloid Cell Leukemia Sequence 1 Protein<br/>Neoplasm Proteins--metabolism<br/>Proteins--metabolism<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>Reactive Oxygen Species--metabolism<br/>U937 Cells<br/>X-Linked Inhibitor of Apoptosis Protein