TY  - GEN
AU  - Baki,Lia
AU  - Shioi,Junichi
AU  - Wen,Paul
AU  - Shao,Zhiping
AU  - Schwarzman,Alexander
AU  - Gama-Sosa,Miguel
AU  - Neve,Rachael
AU  - Robakis,Nikolaos K
TI  - PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations
SN  - 0261-4189
PY  - 2005///0616
KW  - Alzheimer Disease
KW  - genetics
KW  - Animals
KW  - Apoptosis
KW  - Blotting, Western
KW  - Cadherins
KW  - metabolism
KW  - Carbamates
KW  - pharmacology
KW  - Cell Line, Transformed
KW  - Cell Survival
KW  - Cell Transformation, Viral
KW  - Dipeptides
KW  - Enzyme Activation
KW  - Enzyme Inhibitors
KW  - Fibroblasts
KW  - Flow Cytometry
KW  - Glycogen Synthase Kinase 3
KW  - antagonists & inhibitors
KW  - Humans
KW  - Membrane Proteins
KW  - Mice
KW  - embryology
KW  - Mice, Knockout
KW  - Mutation
KW  - Phosphatidylinositol 3-Kinases
KW  - chemistry
KW  - Phosphorylation
KW  - Precipitin Tests
KW  - Presenilin-1
KW  - Protein Serine-Threonine Kinases
KW  - Protein Structure, Tertiary
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-akt
KW  - Simplexvirus
KW  - tau Proteins
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1038/sj.emboj.7600251
ER  -