TY - GEN AU - Yamazaki,Tohru AU - Akada,Tetsuya AU - Niizeki,Osamu AU - Suzuki,Takahiro AU - Miyashita,Hiroki AU - Sato,Yasufumi TI - Puromycin-insensitive leucyl-specific aminopeptidase (PILSAP) binds and catalyzes PDK1, allowing VEGF-stimulated activation of S6K for endothelial cell proliferation and angiogenesis SN - 0006-4971 PY - 2004///1123 KW - 3-Phosphoinositide-Dependent Protein Kinases KW - Animals KW - Catalysis KW - drug effects KW - Cell Cycle KW - Cell Division KW - Cell Line KW - Cyclin-Dependent Kinases KW - metabolism KW - DNA KW - biosynthesis KW - Endothelial Cells KW - cytology KW - Enzyme Activation KW - Humans KW - Leucyl Aminopeptidase KW - genetics KW - Male KW - Mice KW - Mutation KW - Neoplasms KW - blood supply KW - Neovascularization, Pathologic KW - Phosphorylation KW - Protein Binding KW - Protein Serine-Threonine Kinases KW - Retinoblastoma Protein KW - Ribosomal Protein S6 Kinases KW - Vascular Endothelial Growth Factor A KW - pharmacology N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1182/blood-2003-12-4260 ER -