TY  - GEN
AU  - Ruchelman,Alexander L
AU  - Kerrigan,John E
AU  - Li,Tsai-Kun
AU  - Zhou,Nai
AU  - Liu,Angela
AU  - Liu,Leroy F
AU  - LaVoie,Edmond J
TI  - Nitro and amino substitution within the A-ring of 5H-8,9-dimethoxy-5-(2-N,N-dimethylaminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: influence on topoisomerase I-targeting activity and cytotoxicity
SN  - 0968-0896
PY  - 2005///0111
KW  - Amination
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - Cell Line, Tumor
KW  - DNA
KW  - metabolism
KW  - DNA Topoisomerases, Type I
KW  - Enzyme Inhibitors
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Molecular Conformation
KW  - Molecular Structure
KW  - Naphthyridines
KW  - Nitrogen
KW  - chemistry
KW  - Static Electricity
KW  - Topoisomerase I Inhibitors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1016/j.bmc.2004.03.076
ER  -