Ruchelman, Alexander L <br/><br/>
Nitro and amino substitution within the A-ring of 5H-8,9-dimethoxy-5-(2-N,N-dimethylaminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: influence on topoisomerase I-targeting activity and cytotoxicity.  [electronic resource] 

 -  Bioorganic & medicinal chemistry  Jul 2004 
 - 3731-42 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>0968-0896 
<br/><br/><label>Standard No.: </label>10.1016/j.bmc.2004.03.076  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amination<br/>Antineoplastic Agents--chemical synthesis<br/>Cell Line, Tumor<br/>DNA--metabolism<br/>DNA Topoisomerases, Type I--metabolism<br/>Enzyme Inhibitors--chemical synthesis<br/>Humans<br/>Inhibitory Concentration 50<br/>Molecular Conformation<br/>Molecular Structure<br/>Naphthyridines--chemical synthesis<br/>Nitrogen--chemistry<br/>Static Electricity<br/>Topoisomerase I Inhibitors