TY  - GEN
AU  - Yajima,Hiroaki
AU  - Ikeshima,Emiko
AU  - Shiraki,Maho
AU  - Kanaya,Tomoka
AU  - Fujiwara,Daisuke
AU  - Odai,Hideharu
AU  - Tsuboyama-Kasaoka,Nobuyo
AU  - Ezaki,Osamu
AU  - Oikawa,Shinichi
AU  - Kondo,Keiji
TI  - Isohumulones, bitter acids derived from hops, activate both peroxisome proliferator-activated receptor alpha and gamma and reduce insulin resistance
SN  - 0021-9258
PY  - 2004///1025
KW  - Aged
KW  - Animals
KW  - Blood Glucose
KW  - analysis
KW  - Body Weight
KW  - drug effects
KW  - Cyclopentanes
KW  - pharmacology
KW  - DNA-Binding Proteins
KW  - Diabetes Mellitus, Type 2
KW  - blood
KW  - Dietary Fats
KW  - administration & dosage
KW  - Double-Blind Method
KW  - Fatty Acids, Nonesterified
KW  - Female
KW  - Glycated Hemoglobin
KW  - Humans
KW  - Humulus
KW  - chemistry
KW  - Insulin Resistance
KW  - physiology
KW  - Lipoprotein Lipase
KW  - genetics
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Middle Aged
KW  - Pilot Projects
KW  - Pioglitazone
KW  - Placebos
KW  - Plant Extracts
KW  - RNA, Messenger
KW  - Receptors, Cytoplasmic and Nuclear
KW  - Recombinant Fusion Proteins
KW  - Saccharomyces cerevisiae Proteins
KW  - Thiazolidinediones
KW  - Transcription Factors
KW  - Transfection
KW  - Triglycerides
KW  - Weight Gain
N1  - Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial
UR  - https://doi.org/10.1074/jbc.M403456200
ER  -