TY - GEN AU - Höti,Naseruddin AU - Zhu,De-E AU - Song,Zhiyin AU - Wu,Zhengsheng AU - Tabassum,Sartaj AU - Wu,Mian TI - p53-dependent apoptotic mechanism of a new designer bimetallic compound tri-phenyl tin benzimidazolethiol copper chloride (TPT-CuCl2): in vivo studies in Wistar rats as well as in vitro studies in human cervical cancer cells SN - 0022-3565 PY - 2004///1215 KW - Animals KW - Apoptosis KW - Apoptosis Regulatory Proteins KW - Carrier Proteins KW - metabolism KW - Caspase 3 KW - Caspases KW - Cell Division KW - drug effects KW - Cytochromes c KW - Down-Regulation KW - Enzyme Activation KW - Female KW - HeLa Cells KW - Humans KW - Inhibitor of Apoptosis Proteins KW - Intracellular Signaling Peptides and Proteins KW - Membrane Proteins KW - Microtubule-Associated Proteins KW - Mitochondria KW - Mitochondrial Proteins KW - Neoplasm Proteins KW - Organotin Compounds KW - pharmacology KW - Papillomaviridae KW - Proto-Oncogene Proteins c-bcl-2 KW - Rats KW - Rats, Wistar KW - Survivin KW - Tumor Suppressor Protein p53 KW - Uterine Cervical Neoplasms KW - pathology KW - bcl-2 Homologous Antagonist-Killer Protein KW - bcl-2-Associated X Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1124/jpet.104.069104 ER -